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Carcinogenesis Inside of a lifetime carcinogenicity analyze completed in B6C3F1 mice, methylphenidate caused a rise in hepatocellular adenomas, and in males only, a rise in hepatoblastomas at a day-to-day dose of roughly sixty mg/kg/day. This dose is approximately two times the MRHD of 60 mg/working day given to little ones on mg/m2 foundation.Like